I use a wacom tablet for 70-80% of my designs (http://www.wacom.eu/index2.asp?pid=8005). As Artticulas said it takes some time to get used to it… but when you do you can’t do without it. Very handy, practical and precise. My opinion and some fellow designers i know is that tablet is a time saver and get’s your design to the next level… Even better offcourse are these babies but they cost a “little bit” more… http://www.wacom.com/en/Products/Cintiq.aspx
Doru if you feel pain in your wrist while you work…be carefull man. Take a rest or holidays. I had pain in my wrist last june and in the end i went to hospital and they put my hand in plaster for a month. It’s called “Disease Carpal Tunnel”. Disease of computer people (repeated moves). After that i changed to tablet and when i use keyboard/mouse i always have a special pillow under my wrists. (http://www.amazon.com/Kensington-Wrist-Pillow-Keyboard-Black/dp/B00004Z5N5)